Abstract: This paper concerns the determination of stress tensor from a set of striated faults and of focal mechanisms of earthquakes. The central and occidental parts of the North Anatolian Fault Zone illustrates the applied methodology. Then, temporal changes intectonic regimes of the central North Anatolian Fault Zone are briefly examined. The fault kinematics analysis within central North Anatolian Fault shows that strike-slip stress changes from transpressional regime to transtensional regime as indicated by chronologies of fault slip vectors. Both states have consistent NW- and NE- trending o) and O3 axes respectively, but havesignificantly different mean R values: Rm=0.75 for transpressional and Rm=024 for transtensional regimes respectively. Theinversion of focal mechanisms, occurred in the central and occidental parts of North Anatolian Fault Zone, shows that actual stress rejime is transtensional and is characterized by a NW-(N126°E) trending a} and a NE-(N217E) trending a3 axes with a R value of0.40. The stress changes along the North Anatolian Fault Zone result from the coeval influence of forces acting in the west and in theeast. However, the timing of the temporal stress change permits to suggest that Quaternary stress regime variation in central North Anatolian Fault Zone is mainly due to the Aegean domain influence.