Abstract: Northwestern Anatolia contains many active fault segments with different strikes, tectonic regimes andslip rates. In this study, the tectonic control on topography along the Yalakdere Fault, a right-lateral strike-slipfault located south of the Gulf of İzmit, is investigated using a multi-scale morphometric approach. Mountain frontmorphology (Smf, Vf), basin-scale indices (AF, Bs, HI, HC), channel steepness (ksn), and drainage divide stability(χ) analyses are integrated with river profile inversion modeling to constrain the spatial and temporal variability ofuplift. Results reveal significant morphotectonic contrasts between the southwestern and northeastern segments ofthe fault. River profile inversion results show that uplift rates have varied throughout the Pleistocene, with peakuplift occurring during the Early Pleistocene. These findings demonstrate that the morphotectonic evolution of theYalakdere Fault is controlled by fault segmentation, lithological variability and differential uplift. The results furtherindicate that tectonic forcing, rather than climatic variability, represents the dominant control on landscape evolution.